The SMDC offers a challenging and rewarding work environment located in a state-of-the-art facility at the new UCSF Mission Bay campus.
Jobs Currently Available
Specialist/Manager
of High-throughput
Screening
UCSF
A Specialist position is available at the Small Molecule Discovery Center (SMDC) in the Department of Pharmaceutical Chemistry at the University of California, San Francisco (Mission Bay Campus). The SMDC includes an existing high-throughput screening (HTS) center and a chemistry lead-optimization group. The SMDC is currently developing capabilities in fragment discovery and siRNA-based screening and building a grant-supported group focused on drug-discovery research.
The successful candidate will manage the HTS facility with the possibility of managing the fragment discovery and/or siRNA activities. The candidate will oversee the daily operations of the screening center. Responsibilities include managing personnel, purchasing and maintaining equipment, curating the compound libraries, managing budgets, and collaborating with the users of the HTS facility.
Required Qualifications
The incumbent
must have
a Ph.D. in
a relevant
field of
chemistry,
biochemistry,
biology,
or engineering
and 3+ years
experience
with high-throughput
screening.
Strong management
skills and
a desire
to engage
in team-based
research
and collaboration
are required.
Preferred
Qualifications
Pharmaceutical
experience
in drug discovery
is preferred.
A strong background
in bioinformatics,
technology
development,
and/or assay
development
is highly preferred.
The University
of California
seeks candidates
whose experience,
teaching, research,
or community
service has
prepared them
to contribute
to our commitment
to diversity
and excellence.
This position will report to Dr. Michelle Arkin, Associate Director of Biology at the SMDC. The director of the SMDC is Professor Jim Wells. The position is available effective immediately. Salary is commensurate with experience. Please send curriculum vitae and contact information for three references to:
SMDC HTS Manager
Search
c/o Barbara
Raymond
Department
of Pharmaceutical
Chemistry
University
of California,
San Francisco
600 16th Street,
MC 2280
Genentech Hall,
Room 518
San Francisco,
CA 94158-2517
Barbara@picasso.ucsf.edu
Postdoctoral researcher, fragment-based ligand discovery
UCSF
A postdoctoral position is available at the Small Molecule Discovery Center (SMDC) in the Department of Pharmaceutical Chemistry at the University of California, San Francisco (Mission Bay Campus). The SMDC includes an existing high-throughput screening (HTS) center and a chemistry lead-optimization group. The SMDC is currently developing capabilities in fragment discovery and building a grant-supported group focused on drug-discovery research.
We are looking for a postdoctoral scientist to develop fragment-based screening technology. This work requires strong knowledge of protein chemistry and biophysics. Techniques will include protein expression, high-throughput surface Plasmon resonance, other biophysical tools such as analytical ultracentrifugation or calorimetry, and structural tools such as NMR and x-ray crystallography. Research will be highly collaborative with other members of the SMDC and research groups throughout UCSF.
Required Qualifications
The incumbent must have 3+ years experience with protein
chemistry, biophysics, or structural biology and a Ph.D.
in a relevant field of chemistry or biology. Desire and
ability to engage in team-based research and collaboration
is required.
Preferred Qualifications
Experience with some biophysical methods such as surface
plasmon resonance, analytical ultracentrifugation, NMR, or
X-ray crystallography is required; other techniques will be
learned through the position. The University of California
seeks candidates whose experience, teaching, research, or
community service has prepared them to contribute to our
commitment to diversity and excellence.
This position will report to Dr. Michelle Arkin, Associate Director of Biology at the SMDC. The director of the SMDC is Professor Jim Wells. The position is available effective immediately. Salary is commensurate with experience. Please send curriculum vitae and contact information for three references to:
Postdoctoral researcher
c/o Michelle Arkin
Department of Pharmaceutical
Chemistry
University of California, San
Francisco
600 16th Street, MC 2552
Genentech Hall, Room 503E
San Francisco, CA 94158-2517
michelle.arkin@ucsf.edu
