Small Molecule Discovery Center
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Chemistry Core

The Chemistry Core is a fully-integrated component of the SMDC, comprising an experienced team of medicinal chemists and industry-seasoned leadership. Our chemists analyze screening data to identify preliminary structure-activity relationships (SAR), provide analytical and synthetic support during hit validation studies, and conduct hit-to-lead chemistry efforts around those targets/screens that yield particularly interesting and advanceable hits. Resources permitting, the SMDC Chemistry Core is also available to perform custom synthesis for UCSF investigators on a fee for service basis or to advise investigators in the selection of a suitable external vendor for their custom synthesis needs.

Chemistry Contact: Adam Renslo
Tel: (415) 514-9698
Fax: (415) 514-4507

For more information about the capabilities and functions of the SMDC chemistr group, please see Medicinal Chemistry and Custom Synthesis.