The SMDC compound collection was purchased from various commercial vendors. An outline of the collection in PDF form can be downloaded. Plates are available for screening in batches of thirty-two 384 well plates or one hundred twenty-five 96 well plates. Our standard plating protocol is to deposit a total of 80 compounds in 96 well plates, and 320 compounds in 384 well plates. Users can pick compounds to screen only in blocks of whole plates, we do not currently permit users to choose compounds of interest at the well level.